Abstract
L-asparaginase (EC.3.5.1.1, L-asparagine amidohydrolase, L-ASNase) is an enzyme capable to hydrolyze asparagine, which makes it an important biopharmaceutical in the therapy of acute lymphoblastic leukemia (ALL), since the breakdown of this amino acid in the extracellular environment leads to the death of cancer cells that are unable to synthesize it. Even though there are several microor…