CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelors degree in Biochemical Pharmacy from the School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara (2022). Participated in undergraduate research projects in Analytical Chemistry (Institute of Chemistry, UNESP, 20172018) and Pharmaceutical Chemistry (Lapdesf, School of Pharmaceutical Sciences, UNESP, 2021).Masters degree in Pharmaceutical Sciences, with an emphasis in Pharmaceutical Chemistry, from Lapdesf (School of Pharmaceutical Sciences, UNESP), under the supervision of Prof. Dr. Jean Leandro dos Santos. Conducted a research internship at University College London (UCL) under the supervision of Prof. Dr. Daniele Castagnolo, focusing on organic synthesis and characterization of bioactive compounds.Currently a Ph.D. student in the same graduate program (School of Pharmaceutical Sciences, UNESP), with a FAPESP scholarship. The project focuses on the synthesis and pharmacological evaluation of modulators of the ClpP1P2 proteases of Mycobacterium tuberculosis, within the BacPROTAC strategy. The study aims to develop new nitroimidazooxazole derivatives with potential activity against multidrug-resistant strains of M. tuberculosis. (Source: Lattes Curriculum)
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Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb), which still poses a significant challenge to Public Health, mainly due to the emergence of multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains. According to the World Health Organization (WHO), in 2022, approximately 7.5 million new cases of TB were diagnosed, with 1.3 million d…
Although the treatment of tuberculosis (TB) has been made advances in recent years, it can be noted huge challenges such as the emergence of resistant strains become difficult the goals to achieve the eliminating the disease soon. According to the World Health Organization (WHO), in 2018 about 10 million new cases were diagnosed and around 1.2 million deaths occurred. Among the new cases,…
The rising number of tuberculosis (TB) cases and the emergence of resistant strains particularly multidrug-resistant TB [MDR-TB] and extensively drug-resistant TB (XDR-TB) have been motivated the search for new safe and effective drugs. Nitroreductases comprises enzymes responsible for defending Mtb's against exogenous small molecules contributing to the antinitrosative defenses on which …
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