CV Lattes
ORCID
Abstract
Lung cancer is the second most common type of cancer and the main cause of cancer-related death worldwide. The high mortality is associated to late detection of the disease when most of patients already display distant metastases, reducing the overall 5-year survival to 20%.The main oncogenic pathway is MAPK with mutations in KRAS and EGFR, and high prevalence of inactivating mutations in…