Abstract
Barrett's esophagus (BE) is described as the replacement of the squamous epithelium of the esophageal mucosa by a columnar epithelium with goblet cells in the distal portion of the esophagus, characterizing a special intestinal metaplasia. In this context, gastroesophageal reflux disease (GERD) is the main predisposing factor for the appearance of BE, due to the constant aggressions to wh…