Has experience in General Biology (Source: Lattes Curriculum)
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Leukemias are hematologic neoplastic diseases, which are characterized by the uncontrolled proliferation of hematopoietic cells and are classified according to the phenotype of the affected cell. In this study, we will focus on acute promyelocytic leukemia (APL), belonging to the group of acute myeloid leukemia (AML), subgroup M3 or M3 variant. LPA is characterized by a t(15;17) chromosom…
Acute Promyelocytic Leukemia (APL) is characterized by presence of the chromosomal translocation t(15;17) which generates the PML RARA fusion protein. All-trans retinoic acid (ATRA) is one of the main components used for APL treatment. Mutations in the ligand-binding domain (LBD) of the fused RARa nuclear receptor have been associated to ATRA resistance. We sequenced diagnostic and relaps…
| 1 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 2 / 2 | All Scholarships |
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