, acting on the following subjects: doenças cardiovasculares. (Source: Lattes Curriculum)
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Aging is the most significant demographic risk factor for cancer development, indicating that molecular changes during the process are a trigger for malignant transformation. Melanoma is a cancer with a high probability of metastasis and a high rate of resistance to conventional therapies, resulting in a worse prognosis especially for the elderly. Physiological processes such as the accum…
Melanoma is the most lethal type of skin cancer because it is more metastatic and has a high rate of resistance to conventional therapies, which results in a worse prognosis, especially in the elderly. About 50% of melanoma casa involve a mutation in the BRAF gene, in which valine is replaced by glutamic acid at codon 600. In melanoma there is a reduction in Hippo pathway signaling and th…
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