Abstract
Acute respiratory distress syndrome (ARDS) associated with malaria is due to an intense inflammatory response in the lungs. Granzymes and perforins released by parasite-specific CD8+ T cells disrupt the alveolar-capillary barrier, resulting in fluid leakage into the lung interstitial space and, consequently, hypoxia. In this context, there is release of adenosine triphosphate molecules in…