CV Lattes
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Universidade de São Paulo (USP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Pharmacy, University Center of Grande Dourados in 2008, obtained a Master in Organic Chemistry at Federal University of Grande Dourados, Mato Grosso do Sul, Brazil in 2013, and a Ph.D. in. School of Pharmaceutical Sciences of Ribeirão Preto, São Paulo, Brazil in 2017. Post-doctorate fellow at Chemistry department, Faculty of Philosophy Sciences and Letters of Ribeirão Preto, São Paulo, Brazil, where she worked mainly in the following subjects: ENANTIOSELECTIVE ANALYSIS, HPLC-UV, HPLC-MS. Currently she is a post doc at the Chemistry Institute, Department of Biochemistry, where she develops projects involving photodynamic damage applied to mimetic models of membranes. In addition, she in carrying out, RNA seq analysis project in search of cell death pathways, autophagy, ferroptosis, mitophagy and necroptosis triggered by PDT in HaCat, in partnership with the Faculty of Medicine of the University of São Paulo Paulo. (Source: Lattes Curriculum)
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Contact-dependent photosensitized oxidation is essential to form molecular pores and allow membrane leakage, through the accumulation of aldehydes from truncated lipids (J. Am. Chem. Soc. 2018, 140 (30), 9606-96151; 2019, 141 (39), 15547-15556). We also found that damage to organelle membranes greatly increases the efficiency of photoinduced cell death (Autophagy 2019, 15 (2), 259-279). W…
Sterols, referred to as the third lipid class, bear the essential triterpenoid scaffold, that ensure fluidity and flexibility to cell membranes, and serve as signaling important molecules crucial in growth, development and differentiation of organisms. The 7-Dehydrocholesterol (7-DHC) is a biosynthetic precursor of cholesterol and vitamin D3, and ergosterol. Similar to the polyunsaturated…
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