Abstract
Coronavirus Disease 2019 (COVID-19) is caused by SARS-CoV-2 virus and has achieved pandemic character at the beginning of 2020. Virus entry in host cells is mediated by spike (S) proteins, which are densely glycosylated proteins present in SARS-CoV-2 envelope, by binding its structure to Angiotensin-Converting Enzyme 2 receptor (ACE-2). Previous studies have shown that this interaction is…