Bachelor of science in Health Sciences (Centro Universitário das Faculdades Metropolitanas Unidas, FMU); Emphasis in Molecular Biology and Clinical Pathology. He was an undergraduate researcher in the Laboratory for Post-Transcriptional Control of Gene Expression at the Institute of Chemistry (IQ) of the University of São Paulo (USP). Internship in Clinical Pathology at the Research Incentive Fund Association (AFIP). Participated in university extension programs. (Source: Lattes Curriculum)
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The small nuclear RNA (snRNA) U2 is an essential component of the spliceosome that interacts directly with conserved sequences in pre-mRNA during splicing. The role of U2 snRNA extends from the assembly of the pre-spliceosome, through its activation and catalysis, to the disassembling of the complex and involves various changes in its structure. The formation of the small nuclear ribonucl…
Most eukaryotic genes contain non-coding sequences, called introns, that are removed during splicing. This maturation process is carried out by the spliceosome in conjunction with hundreds of evolutionarily conserved factors, including the Cwc24 protein, which binds to the 5' end of the intron, protecting it. The binding of Cwc24 to the pre-mRNA and the spliceosome is temporary, but its a…
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CV Lattes
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