CV Lattes
ORCID
Abstract
Sickle cell anemia (SCA) is a disease in which a point mutation in the beta-globin chain (HbB) gene, type A - T, leads to the synthesis of "S" globins and formation of hemoglobins (HbS) that polymerize within the red blood cells, changing their biconcave structure making them sickle. These cells present greater dehydration and endothelial adhesion, in addition to a high degree of hemolysi…