Abstract
This project has the following objectives: (i) to screen the LifeArc library (https://www.lifearc.org/) for compounds that can synergize caspofungin or voriconazole in A. fumigatus wild-type and caspofungin-, and voriconazole-resistant strains (ii) to characterize the mechanisms of action of the most promising compounds found in the LifeArc library, by several tools such as screening of n…