CV Lattes
ORCID
Abstract
The use of proton pump inhibitors (PPIs) has been associated with an increased risk of developing cardiovascular disease. There is evidence that PPIs increases the activity of asymmetric dimethylarginine (ADMA), which is an endogenous inhibitor of nitric oxide (NO). Other studies indicates that omeprazole increases the activity of xanthine oxidoreductase (XOR), promoted by ADMA, causing g…