Undergraduated in Biological Sciences by Universidade de São Paulo, currently studying for a master's degree in the Interunit Postgraduate Program in Bioinformatics - USP, with interest in Molecular Biology and Bioinformatics. He was a PIBIC/USP fellow (08/2021 - 07/2022), and developed a project on computational analysis of RNA sequences, in which he obtained predictions of new secondary structures in the RNA molecule of the FMR1 gene. And was a FAPESP fellow and developed a project on functional analysis of circular transcripts of this gene, on how the alternative splicing can affect in different ways the primary transcript segment of FMR1 between exons 12 and 15. (Source: Lattes Curriculum)
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Fragile X syndrome is due to loss of function of the FMR1 gene, which encodes FMRP, a protein related to neurodevelopment in the central nervous system. Changes in FMRP expression may be deleterious to neurogenesis and synaptic plasticity. Alternative splicing may affect in different ways the FMR1 transcript segment between exon 12 and exon 15. Here we aim to assess the effects of the ove…
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