I am a biomedical scientist with a specialization in molecular biology and immunology. Currently, I am conducting research at the Institute of Biomedical Sciences at the University of São Paulo, under the supervision of Prof. Dr. Niels Olsen, investigating the role of the transcription factor HIF-1a; in the development of type 1 diabetes.Recently, I completed an internship in the laboratory of Prof. Dr. Ari Waisman at the University Medical Center of Mainz, where I further developed my expertise in experimental immunology.My work involves the use of cutting-edge techniques and in-depth data analysis to identify novel therapeutic targets. I am passionate about advancing our understanding of autoimmune diseases and contributing to innovative solutions in the biomedical field. (Source: Lattes Curriculum)
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Type 1 Diabetes Mellitus is an autoimmune disease in which pancreatic ² cells are destroyed by T cells CD8+ and CD4+ that recognize self-antigens. This disease has an alarming raise of cases in the last couple of years. ² cells are responsible for insulin production. That said, loss of ² cells result in hyperglycemia with effects in the nervous system and even death. It has been reported …
HIF-1 is a transcription factor that enables cells to adapt to low oxygen levels through glycolysis. This metabolic plasticity is vital for immune cell survival and differentiation, regulated by HIF-1alpha. HIF-1alpha also influences the balance between Treg and Th17 cells, suggesting metabolic pathways as potential targets for immune-mediated diseases. In addition, NFkB is a critical tra…
| 1 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
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CV Lattes
ORCID