Abstract
It is well established that endothelial cells modulate vascular reactivity through the release of mediators such as prostacyclin, nitric oxide and endothelin. Catecholamines modulate vascular tone through actions on ±- and ²-adrenergic agents, however, the production and release of catecholamines are associated with the existence of nerve endings in vessels. Dopamine, a well-known neurotr…