Abstract
The polycomb complex PRC2/EZH2 is an epigenetic modulator that represses gene expression by trimethylation of histone H3 at lysine 27 (H3K27Me3). In cancer, several studies have reported increased EZH2 expression, especially in aggressive types of cancer. Our previous data show and the literature showed that EZH2 levels are increase in anaplastic thyroid cancer (ATC), the most lethal form…