CV Lattes
ORCID
Abstract
In mammals, proteins belonging to the REST (rapidly-evolving seminal vesicle transcribed) family, secreted by the seminal vesicles, are the most abundant components of the seminal plasma. In humans, the major REST protein is semenogelin-1 (SEMG1), which binds EPPIN on the surface of ejaculated spermatozoa, leading to inhibition of sperm motility that lasts until SEMG1 is cleaved by prosta…