Abstract
Filopodia-like cellular protrusions are observed in most cell types and may carry protein condensates, which eventually detach from them as microvesicles. These processes are highly redox-regulated and our group has identified that protein disulfide isomerase-A1 (PDIA1), a thiol-redox chaperone from the endoplasmic reticulum, is an important component of these protein condensates. PDIA1 i…