Abstract
Fabry disease (FD) is an inborn error of metabolism caused by mutations in the gene for the enzyme ±-galactosidase A (GLA) located on the X chromosome. These mutations result in deficiency of the enzyme ±-galactosidase A (±-Gal A), causing the accumulation of globotriaosylceramide (Gb3). ±-Gal A deficiency results in pathogenic changes in several organs, including Fabry cardiomyopathy, wi…