Abstract
Introduction: The velocardiofacial spectrum syndrome, often caused by the 22q11.2 deletion, affects one in every 2,000 individuals, which makes it one of the most frequent syndromes in humans. Among more than 180 findings present in the spectrum of chromosome 22q11.2 alterations, congenital heart diseases and craniofacial anomalies stands out, in addition to sleep-disordered breathing, wh…