Abstract
Oral squamous cell carcinoma (OSCC) is the sixteenth most common malignant neoplasm worldwide. Despite recent advances in basic and clinical knowledge about OSCC, 50% of the cases have bad prognosis, with relapse and metastasis. The lipid metabolism, particularly the endogenous fatty acid synthesis, is mediated by the anabolic enzyme fatty acid synthase (FASN) and has been shown to be imp…