CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Farmácia Bacharelado (5209) from Universidade Federal do Espírito Santo (2017) and master's at Ciências Farmacêuticas from Universidade Federal do Espírito Santo (2019). , acting on the following subjects: triagem fitoquímica, electrospinning, silver sulfadiazine, wound dressing and sangue-de-dragão. (Source: Lattes Curriculum)
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Glioblastoma multiforme (GBM) is the most aggressive and prevalent variant of glioma. Temozolomide (TMZ), the treatment of first choice, is a prodrug that undergoes hydrolysis at physiological pH to form the methyldiazonic cation responsible for DNA alkylation. TMZ is the only drug available for the treatment of GBM, however, the low half-life of the drug associated with its biopharmaceut…
Glioblastoma Multiforme (GBM) is the most aggressive and prevalent variation of glioma. Temozolomide (TMZ), the standard treatment, is a prodrug that hydrolyzes at physiological pH (> 7.0) to form ion responsible for DNA alkylation. The limited therapeutic efficacy and low survival required alternatives to overcome the therapeutic drawbacks associated with properties of TMZ and the physio…
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