Abstract
Aspergillus fumigatus is the main causative agent of Invasive Aspergillosis (IA), which is considered a serious disease with a high mortality rate, especially in immunocompromised patients. The first drug for treatment is Voriconazole (VRC), which belongs to the azole class. Patients undergoing treatment for AI with VRC are at great risk of A.fumigatus undergoing genetic alterations, whic…