Abstract
Extranodal T/NK cell lymphoma, nasal type (LETNKn) is a rare lymphoid malignancy derived from monoclonal proliferation of CD8+ cytotoxic T lymphocytes or natural killer (NK) cells associated with EBV infection. After infecting T/NK cells, viral oncoproteins stimulate the constitutive activation of different intracellular signaling pathways, such as AKT, JAK/STAT, MAPK and NF-kB, inhibitin…