Abstract
Melanoma is a malignancy associated with melanocytes, and it is more commonly found on the skin. Around 325,000 new cases with an estimated 57,000 deaths occurred worldwide in 2020. The treatment for melanoma is based on chemotherapy with dacarbazine and BRAF and MEK inhibitors, because approximately half of the patients have mutations in the BRAF gene and one-fourth in NRAS. The importan…