Abstract
Prostaglandin E2 (PGE2) is a lipid mediator produced by several cell types, exerting itseffector functions through autocrine and paracrine mechanisms. PGE2 synthesis canoccur constitutively and/or be induced via activating cyclooxygenase enzymes 1 and 2(COX-1 and COX-2), both under physiological conditions and in the context of infectionsor pathological processes. Previous studies have de…