Abstract
Head and neck carcinoma (HNSCC) is a neoplasm with a high incidence rate and aggressiveness, however, the forms of treatment have little specificity, using the same chemotherapy agents for over 50 years. Matriptase is a type II transmembrane serine protease (TTSP), which plays a crucial role in maintaining the physiological functions of epithelial tissues. However, its expression is incre…