PhD candidate at the Institute of Physics of São Carlos (University of São Paulo - USP) with the project "Characterization of the Formation of Functional Solid Condensates of the Neuropeptides CRH and Neuropeptide Y in the Context of Anxiety and Depression" (FAPESP Grant: 2024/10392-8).Bachelor in Physical and Biomolecular Sciences from the Institute of Physics of São Carlos (IFSC-USP), where he conducted studies on the aggregation mechanisms of functional amyloids for neuropeptide Y. In 2023, he won the award for the best poster presentation given by the Brazilian Biophysics Society (SBBF) during the 47th Meeting of the Brazilian Biophysics Society, where he presented the work ELUCIDATING THE MOLECULAR MECHANISMS OF AGGREGATION OF FUNCTIONAL AMYLOIDS FORMED BY HUMAN NEUROPEPTIDE Y. (Source: Lattes Curriculum)
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Structural biology is undergoing a revolution with advancements in cryo-electron microscopy (Cryo-EM) and artificial intelligence (AI), allowing for the unprecedented precision study of high molecular weight proteins and large protein complexes. However, these technologies do not yet fully address intrinsically disordered proteins (IDPs) and their intrinsically disordered regions (IDRs), …
The study of amyloid fibril formation is a fundamental area of research due to its association with various neurodegenerative diseases and the unique ability of several proteins to form these structures, even without shared sequence similarities. This project focuses on the study of the molecular mechanisms of functional amyloid formation, with a focus on neuropeptides like Neuropeptide Y…
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