Abstract
According to the Brazilian Ministry of Health, 28,587 new cases of schistosomiasis were registered in Brazil in 2020, with an estimated total of 6 to 8 million infected individuals. The treatment for this parasitic disease has been carried out using the same anthelmintic drug, Praziquantel, since 1996, which has led to a loss of sensitivity and resistance of Schistosoma mansoni to it in s…