Abstract
Endolysins (ELs) are enzymes produced by bacteriophages that disrupt the peptidoglycan layer (PG) compromising cell integrity. Based on catalytic activity, phage ELs are classified into five superfamilies, glucosaminidases, muramidases, transglycosylases, endopeptidases, and amidases. PG is a structure found only in bacteria making it an excellent target for antibiotics such as penicillin…