CV Lattes
ORCID
Abstract
The cytotoxic T lymphocyte antigen 4 (CTLA-4) is a cellular receptor that plays a fundamental role as an immune checkpoint, responsible for regulating the immune response and preventing an attack against the body's own cells. On the other hand, tumor cells can exploit this pathway to suppress an immune response, and the CTLA-4 inhibitor ipilimumab is successfully used in the treatment of …