Abstract
This study will investigate the effect of functionalization of zirconia discs with collagen associated with hydroxyapatite using an in vitro implantology model and human osteoblasts. Zirconia discs with 8mm-diameter will be obtained and standardized by sand blasts (400, 600, 1200 and 2000). Then, discs will be sterilized in autoclave and subjected to funcionalization with collagen type I …