Abstract
Medulloblastoma (MB) is the most common pediatric malignant tumor of the central nervous system (CNS), representing approximately 20% of CNS tumors in children and adolescents. For these patients, the five-year overall survival (OS) is 40 to 90%, with variations between the molecular subgroups of MB (SHH, WNT, Group 3 and 4), among which Group 3 and SHH with TP53-mutated represent the mos…