Abstract
Spinal cord injury (SCI) triggers inflammatory response modulated by the action of receptors, including Toll-like receptors (TLRs). After SCI, the accumulation of damaged-associated molecular patterns (DAMPs) activates TLRs throughout MyD88 association with the TLR domain. TLR/MyD88 association leads to NF-ºB translocation to the nucleus, inducing the expression of its target genes. There…