Abstract
Palitantin is a secondary metabolite originally isolated from culture media of the fungus Penicillium palitans, and it is also produced by other fungal species. A fungal strain, Penicillium sp. AMF1a, from Antarctica, produces (+)-palitantin with a yield of approximately 170 mg/L, allowing for the isolation of this compound for use in larger-scale preparation of derivatives. The synthetic…