Abstract
The hepatocellular carcinoma (HCC) is a malignant neoplasm of significant epidemiological burden with a poor prognosis. Current HCC therapies, including the universal tyrosine kinase inhibitor sorafenib (SOR), feature low efficacy. Thus, the potential synergy of bioactive compounds from foods, such as caffeic acid (CA), with traditional chemotherapy regimens is still encouraged in the lit…