Abstract
According to the literature, the absence of the pyrin domain of the NLR family (NLRP3) is related to muscle aging and the progression of sarcopenia (1). The NLRP3 inflammasome can be induced by several pathogens and molecular patterns associated with cellular damage and damaged organelles, and its activation stimulates the maturation of pro-inflammatory cytokines, such as interleukin-1² (…