CV Lattes
ORCID
Abstract
The human genome encodes more than 500 protein kinases, of which the majority remain to be explored for their structure and function. Also, there are at least 91 protein kinases that represent likely cancer drivers 1 and dysregulation of kinase function is a hallmark of most human cancers. As a result, kinase inhibitor development has been one of the major focuses of drug development duri…