Abstract
Sickle cell disease (SCD) stands as one of the genetic hematological conditions identified by a point mutation in the beta globin gene. In Brazil, approximately 3,500 individuals are born with SCD annually, and 300,000 carry the sickle cell trait. While there have been advancements in potential curative methods such as allogeneic hematopoietic stem cell transplantation and gene editing, c…