Abstract
Herpes simplex virus (HSV), type 1 (HSV-1) and type 2 (HSV-2), co-evolved with humans and is present in high frequency in the general population, affecting approximately 190 million people worldwide. In general, with a mild or asymptomatic manifestation, it can cause serious neonatal infections, developing encephalitis and keratitis. Furthermore, neuroinflammation/immunosenescence with th…