Abstract
The overconsumption of saturated fats in the diet leads to the chemotaxis of immune cells to various tissues, including the hypothalamus, the central regulator of energy homeostasis. In mice, the consumption of a high-fat diet (HFD) results in endothelial dysfunction of fenestrated capillaries, found in the median eminence (ME), and the blood-brain barrier (BBB), which is distributed thro…