Abstract
Hypoxia is defined as a decrease in tissue O2 concentration and ischemia as a decrease in blood flow to the tissue which, in turn, prevents the adequate distribution of O2, glucose and other nutrients. Hypoxia is one of the most potent stimulators of vascular endothelial growth factor (VEGF). Hypoxic-ischemic encephalopathy, mainly resulting from oxygen deprivation at birth, whose clinica…