Abstract
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm that accounts for approximately 15% of all leukemia cases diagnosed in adults. While in the past the mortality rate was 10-20%, today it reaches around 1-2%. The disease is characterized by the presence of the Philadelphia chromosome, which is the result of a reciprocal translocation between the long arms of chromosomes 9 (ch…