Abstract
The Xia-Gibbs syndrome (XGS, OMIM #615829) is a neurodevelopmental disorder caused by pathogenic variants in heterozygosity in the AHDC1 gene. The main clinical features of XGS include hypotonia, motor and speech delay, and intellectual disability. The pathophysiology of XGS is not fully understood, requiring additional functional studies. We developed a zebrafish (Danio rerio) model with…