CV Lattes
ORCID
Abstract
Periodontitis is an immunoinflammatory disease characterized by recruitment of immune system cells that release mediators, such as tumour necrosis factor-alpha (TNF-±), interleukin-1² (IL-1²), IL-6 and matrix metalloproteinases. These cytokines promote degradation of extracellular matrix components as well as osteoclast formation and activity, culminating in the bone loss. Therefore, the …