Abstract
In humans, influenza is caused by influenza viruses (IVs), predominantly types A (IAV) and B (IBV), and constitutes a global public health problem, responsible for 3 to 5 million cases and 290 to 650 thousand deaths annually worldwide. IAVs have been responsible for various pandemics throughout history, such as the Spanish flu pandemic, Asian flu, swine flu, among others. Currently, exist…