Abstract
The aim of this project will be to evaluate the process of bone modulation in the progression of periodontal disease induced with or without the use of bisphosphonate. The animals will be randomly divided into 2 groups (7 animals in each group; n=7 ligatures/group): Control (C): The animals will be given serum daily. Bisphosphonate group (BIS): the animals will be given bisphosphonate (1m…