Abstract
The conversion of Cysteine (Cys) to Pyruvate (Pyr) can be carried out by two enzymes: a broad-spectrum substrate Aspartate aminotransferase (ASAT), which includes Cys among its substrates, and a Mercaptopyruvate Sulfotransferase (MPST). Due to their characteristics, the ASAT enzymes in T. cruzi are potential candidates for catalyzing the deamination reaction of Cys. However, despite the e…