CV Lattes
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Universidade Federal do ABC (UFABC). Centro de Ciências Naturais e Humanas (CCNH) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Pharmacist and Postdoctoral Researcher at UFABC, utilizing zebrafish as a neuropharmacology model. Holds a PhD in Sciences from the Biochemistry Laboratory at the Instituto Butantan, a Master's in Pharmaceutical Sciences from the Federal University of Sergipe, and a Bachelor's from the Federal University of Alagoas.Experienced in analytical methods (HPLC, MALDI-TOF, mass spectrometry), animal models (mice and zebrafish), in vitro assays, project management, teaching, genetic editing (morpholino, CRISPR/Cas-9), and toxicological/pre-clinical tests. Contributes to advancing knowledge on toxins and venoms of venomous animals, developing antivenoms and drugs. Focused on applying scientific knowledge to improve quality of life. (Source: Lattes Curriculum)
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Neuroprotection mediated by proline-rich oligopeptides (PROs), derived from Bothrops jararaca snake venom, has been reported when different neuronal cell cultures are pre-treated with PROs and then exposed to oxidative stress. The neuroprotection of PRO-10c (<ENWPHPQIPP) is related to the increased synthesis of L-arginine, its metabolism and the formation of agmatine and polyamines which …
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